Abstract Transcription factor binding sites (TFBSs) are important sources of evolutionary innovations.Understanding how evolution navigates the sequence space of such sites can be achieved by mapping TFBS adaptive landscapes.In such a landscape, an individual location corresponds to a TFBS bound by a transcription factor.The elevation at that locat
Onboard quarantining has been only partially effective to control outbreaks of coronavirus disease on cruise ships.We describe the successful use of the ship as a quarantine facility during the response to the outbreak on the MS Artania, which docked in Western Australia, Australia.The health-led 14-day Filter quarantine regime was based on establi
We report the finding of alkaline phosphatase-immunoglobulin complex (macro-alkaline phosphatase (macro-ALP)) in a patient with persistently increased ALP activity.The Acid Neutralizing Formulas identification of macro-ALP is important to rule out pathological causes of increased ALP activity and to avoid unnecessary diagnostic investigation.The pa
Many infectious diseases arise from co-infections or re-infections with more than one genotype of the same pathogen.These mixed infections could alter host fitness, the severity of symptoms, success Rice Cakes in pathogen transmission and the epidemiology of the disease.Trypanosoma cruzi, the etiological agent of Chagas disease, exhibits a high bio